Serum MOG-IgG in children meeting multiple sclerosis diagnostic criteria.

Giulia FaddaPatrick WatersMark WoodhallRobert A BrownJulia O'MahonyDenise A CastroGiulia LongoniE Ann Yeh Kathryn C Fitzgerald Douglas Lorne ArnoldBrenda BanwellAmit Bar-Or

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)

While children with MOG-IgG can have clinical, CSF, and MRI features conforming to MS criteria, the presence of MOG-IgG is associated with atypical features and predicts a non-MS disease course. Given MOG-IgG seropositivity can wane over time, testing at first attack is of considerable importance for the diagnosis of MOGAD.

Keyphrases

multiple sclerosis
mass spectrometry
young adults
ms ms
magnetic resonance imaging
white matter
contrast enhanced
magnetic resonance