Login / Signup

Metabolically healthy versus unhealthy obesity and risk of fibrosis progression in non-alcoholic fatty liver disease.

Yejin KimYoosoo ChangYong Kyun ChoJiin AhnHocheol ShinSeungho Ryu
Published in: Liver international : official journal of the International Association for the Study of the Liver (2019)
In the large-scale cohort of young and middle-aged individuals with NAFLD, BMI was positively associated with worsening of noninvasive fibrosis marker regardless of metabolic health status. Excess adiposity per se, even without accompanying metabolic health status, may contribute to fibrosis progression in NAFLD.
Keyphrases
  • middle aged
  • weight gain
  • insulin resistance
  • liver fibrosis
  • body mass index
  • metabolic syndrome
  • type diabetes
  • weight loss
  • skeletal muscle
  • high fat diet induced
  • physical activity