Omeprazole and adenocarcinoma in the stomach of rats submitted to duodenogastric reflux. Is there a protective effect?
Rosângela Lucinda Rocha MonteiroMaria Aparecida Marchesan Rodrigues KobayasiMarina Rachel de AraujoDafny Rocha MonteiroNelson Adami AndreolloPublished in: Acta cirurgica brasileira (2020)
The occurrence of squamous hyperplasia, adenomatous hyperplasia and adenocarcinoma increased after gastrojejunal anastomoses, which cause duodenogastric reflux. The association of omeprazole did not protect the development of proliferative lesions and cancer induced by duodenogastric reflux in rats.