Premalignant Conditions of Bone.
Michael D EckhoffMatthew E WellsOsvaldo PadillaElizabeth M PolferChristopher J CastagnoAhmed M ThabetShaimaa ElzamlyHarry L WilsonRajiv RajaniPublished in: Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews (2022)
Development of malignancy is a multifactorial process, and there are multitude of conditions of bone that may predispose patients to malignancy. Etiologies of malignancy include benign osseous conditions, genetic predisposition, and extrinsic conditions. New-onset pain or growth in a previously stable lesion is that should concern for malignant change and should prompt a diagnostic workup for malignancy.