Dried blood spots from finger prick facilitate therapeutic drug monitoring of adalimumab and anti-adalimumab in patients with inflammatory diseases.

Eva L KneepkensMieke F PouwGerrit Jan WolbinkTiny SchaapMichael T NurmohamedAnnick de VriesTheo RispensKarien Bloem

Published in: British journal of clinical pharmacology (2017)

We show here for the first time that adalimumab and ADA serum concentrations can be satisfactorily estimated by measuring concentrations in DBS eluates, collected by finger prick. This method offers great opportunity to simplify TDM of adalimumab.

Keyphrases

rheumatoid arthritis
juvenile idiopathic arthritis
hidradenitis suppurativa
ulcerative colitis
disease activity
oxidative stress
deep brain stimulation
systemic lupus erythematosus