Intestinal Microbial Products From Alcohol-Fed Mice Contribute to Intestinal Permeability and Peripheral Immune Activation.
Derrick R SamuelsonMin GuJudd E ShellitoPatricia E MolinaChristopher M TaylorMeng LuoDavid A WelshPublished in: Alcoholism, clinical and experimental research (2019)
Collectively, these data suggest that microbial products contribute to immune activation and intestinal permeability associated with alcohol dysbiosis. Further, utilization of these ex vivo microbial product assays will allow us to rapidly assess the impact of microbial products on intestinal permeability and immune activation and to identify probiotic therapies to ameliorate these defects.