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Effects of cyclosporin, nifedipine and phenytoin on gingival myofibroblast transdifferentiation in monkeys.

Claudia Misue KannoJose Americo de OliveiraEdilson ErvolinoAna Maria Pires Soubhia
Published in: Journal of applied oral science : revista FOB (2018)
Based on this methodology, it may be concluded that gingival overgrowths induced by cyclosporin, nifedipine and phenytoin are not associated with neither myofibroblast transdifferentiation, proliferation nor apoptosis of gingival connective cells in monkeys.
Keyphrases
  • cell cycle arrest
  • induced apoptosis
  • cell death
  • transforming growth factor
  • endoplasmic reticulum stress
  • signaling pathway
  • oxidative stress
  • pi k akt
  • pulmonary fibrosis
  • cell proliferation