CAR-T cells beyond CD19, UnCAR-Ted territory.

Published in: American journal of hematology (2019)

CAR-T cells have made dramatic inroads in targeting CD19-positive B-cell malignancies. This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia.

Keyphrases

acute myeloid leukemia
induced apoptosis
nk cells
cancer therapy
diffuse large b cell lymphoma
cell proliferation
drug delivery
hodgkin lymphoma