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Validation of loop-mediated isothermal amplification for the detection of Loa loa infection in Chrysops spp in experimental and natural field conditions.

Glory Ngongeh AmamboRaphael Awah AbongFanny Fri FombadAbdel Jelil NjouendouFranck NietchoAmuam Andrew BengRitter ManuelMathias Eyong EsumKebede DeribeJerome Fru ChoPeter Ivo EnyongCatherine PooleAchim HoeraufClotilde CarlowSamuel Wanji
Published in: Parasites & vectors (2021)
This study demonstrated the potential of LAMP as a simple surveillance tool. It was found to be more sensitive than microscopy for the detection of experimental and natural L. loa infections in Chrysops vectors.
Keyphrases
  • loop mediated isothermal amplification
  • sensitive detection
  • public health
  • high resolution
  • single molecule
  • high throughput
  • optical coherence tomography
  • risk assessment
  • mass spectrometry
  • human health
  • single cell