Pediatric asthma: An unmet need for more effective, focused treatments.
Papadopoulos G NikolaosAdnan ČustovićMichael D CabanaSharon D DellAntoine DeschildreGunilla HedlinElham HossnyPeter Le SouëfPaolo Maria MatricardiAntonio NietoWanda PhipatanakulPaulo M PitrezPetr PohunekMarcela GavornikovaXavier JaumontDavid J PricePublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2018)
There is a need for a uniform definition of pediatric asthma, clearly distinguishable from adult asthma. Furthermore, guidelines which provide specific treatment recommendations for the management of pediatric asthma are also needed. Clinical trials and real-world evidence studies assessing anti-immunoglobulin E (IgE) therapies and other monoclonal antibodies in children <6 years of age with asthma may provide further information regarding the most appropriate treatment options in these vulnerable patients. Early intervention with anti-IgE and non-steroid-based alternative therapies may delay disease progression, leading to improved clinical outcomes.