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Evidence for ABL Amplification in Multiple Myeloma and Therapeutic Implications.

He HuangShuping ZhouHongdou LinWenjian GuoYing LinRonxin YaoLicai HeKang YuQian Li
Published in: Journal of oncology (2022)
Our study firstly discussed ABL gene amplification was prevalent in MM cells, and we believe that the ABL gene would potentially be a useful target in the treatment of combination strategy for MM with ABL amplification in the future.
Keyphrases
  • tyrosine kinase
  • chronic myeloid leukemia
  • nucleic acid
  • multiple myeloma
  • copy number
  • induced apoptosis
  • genome wide
  • label free
  • genome wide identification
  • signaling pathway
  • transcription factor