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Safety and Efficacy of Coma Induction Following First-Line Treatment in Status Epilepticus: A 2-Center Study.

Pia De StefanoSira Maria BaumannSaskia SemmlackStephan RüeggStephan MarschMargitta SeeckRaoul Sutter
Published in: Neurology (2021)
This study provides Class III evidence that early induction of artificial coma after unsuccessful first-line treatment for SE is associated with shorter duration of SE and ICU and hospital stays compared to the use of a second-line nonanesthetic antiseizure drug instead of or before anesthetics, without an associated increase in complications.
Keyphrases
  • healthcare
  • intensive care unit
  • emergency department
  • mechanical ventilation
  • drug induced
  • extracorporeal membrane oxygenation
  • electronic health record