Renal Regional Oxygen Saturation (rSrO2) and Acute Kidney Injury in neonates with perinatal asphyxia.

Ninety-one patients were included in the study. On an average, patients with AKI exhibit lower rSrO2 levels during therapeutic hypothermia. Specifically, rSrO2 levels within the first 12 h and between 25 and 72 h of therapeutic hypothermia demonstrated the highest predictive capability for AKI. Multivariate logistic regression analysis revealed that rSrO2 levels within the initial 12 h (adjusted odds ratio [aOR] 1.11, 95% CI 1.01 - 1.21) and between 61 and 72 h (aOR 0.85, 95% CI 0.78 - 0.92) were significantly associated with AKI.