Determination of anti-ADAMTS-13 autoantibody titers in ELISA: Influence of ADAMTS-13 presentation and autoantibody detection.

Charlotte DekimpeElien RooseKadri KangroQuintijn BonnezAline VandenbulckeEdwige TellierGilles KaplanskiHendrik B FeysClaudia TersteegAndres MännikSimon F De MeyerKaren Vanhoorelbeke

Published in: Journal of thrombosis and haemostasis : JTH (2021)

Anti-ADAMTS-13 autoantibody levels using different methods of rADAMTS-13 presentation strongly correlate. However, the levels of anti-ADAMTS-13 autoantibodies are highly dependent on the detection antibody used, which should detect all IgG subclasses (IgG1-4 ) equally well.

Keyphrases

systemic lupus erythematosus
label free
real time pcr
molecularly imprinted
quantum dots
sensitive detection