Nickel-Catalyzed Reductive anti -Arylative Cyclization of Alkynyl Enones with Aryl Halides.

A nickel-catalyzed reductive anti -arylative cyclization of alkynyl enones with aryl halides has been developed. The reaction avoids the use of stoichiometric organometallic reagents and has a broad reaction scope and high functional group tolerance. This method offers an efficient way to access a variety of synthetically useful carbocycles that are widely found in many natural products and biologically active molecules.