Near complete remission of an inoperable pancreatic acinar cell carcinoma after BRAF-/MEK-inhibitor treatment-A case report and review of the literature.

Lennart von Fritsch Nikolas von BubnoffKlaus WeberJutta KirfelCleopatra SchreiberTobias KeckUlrich Wellner

Published in: Genes, chromosomes & cancer (2024)

Studies suggest that up to one-fourth of PACCs carry a BRAF mutation and might therefore be susceptible to a BRAF-/MEK-inhibitor therapy. This offers a new therapeutic pathway to treat this rare but malignant neoplasm.

Keyphrases

metastatic colorectal cancer
wild type
pi k akt
low grade
disease activity
rheumatoid arthritis
case control
replacement therapy
ulcerative colitis
high grade
rectal cancer