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Association of Attenuated Niacin Response With Inflammatory Imbalance and Prediction of Conversion to Psychosis From Clinical High-risk Stage.

TianHong ZhangXuDong XiaoHaiSu WuJiaHui ZengJiaYi YeYuQing GaoYeGang HuLiHua XuYanYan WeiXiaoChen TangHaiChun LiuTao ChenXiaoHua LiuChunBo LiLinLin ZhouXuMing WuJiJun Wang
Published in: The Journal of clinical psychiatry (2023)
Conclusions: Our findings indicate a significant association between niacin response and psychosis conversion outcomes in individuals with CHR. Compared with peripheral inflammatory cytokines, the niacin response can better predict conversion, although there may be an intersection between the two in biological mechanisms.
Keyphrases
  • oxidative stress
  • metabolic syndrome
  • skeletal muscle
  • weight loss
  • chemotherapy induced