Enhanced Turn-On Fluorescence Detection of Aqueous Lead Ions with Size-Shrinkable Hydrogels.

Highly sensitive detection of lead ions in water is of importance. This paper reports a new method to enhance the sensitivity of fluorescence detection of aqueous lead ions by exploiting the large volume reduction of hydrogels upon dehydration. Rhodamine-derived prefluorescent probes with high selectivity to lead ions are grafted on a carboxylated agarose hydrogel. Upon binding low-concentration lead ions, fluorescence emission is turned on. The dehydration of the hydrogel leads to a size reduction of over 40 times and an enhancement of fluorescence of 10 times at a lead-ion concentration of 10-7 M, allowing fluorescence detection with naked eyes. Given its low cost, easy operation, and high sensitivity, the volume reduction hydrogel can be used to detect lead ions in drinking water.