Plasma levels of direct oral anticoagulants in atrial fibrillation patients at the time of embolic stroke: a pilot prospective multicenter study.

Vladimír NosáľAndrea PetrovičováIngrid ŠkorňováTomáš BolekJana DluháLucia StančiakováŠtefan SivákLucia BabálováGabriel HajašJán StaškoPeter KubiszEgon KurčaMatej SamošMarián Mokáň

Published in: European journal of clinical pharmacology (2022)

This observational study showed significantly lower anti-IIa and anti-Xa plasma levels in AF patients with embolic stroke compared to those who tolerated long-term therapeutic dose DOAC therapy.

Keyphrases

atrial fibrillation
direct oral anticoagulants
oral anticoagulants
catheter ablation
left atrial
left atrial appendage
heart failure
percutaneous coronary intervention
venous thromboembolism
study protocol
clinical trial
stem cells
brain injury
left ventricular