Association between Interferon-Lambda-3 rs12979860, TLL1 rs17047200 and DDR1 rs4618569 Variant Polymorphisms with the Course and Outcome of SARS-CoV-2 Patients.
Sara Hassan AgwaMarwa Mostafa KamelHesham ElghazalyAya M Abd ElsameeHala HafezSamia Abdo GirgisHoda Ezz ElarabFatma S E EbeidSafa Matbouly SayedLina SherifMarwa MatboliPublished in: Genes (2021)
Among people who carry C and A alleles of SNPs IFN-λ rs12979860 and TLL1 rs17047200, respectively, the AG genotype of the DDR1 rs4618569 variant is correlated with a COVID-19 poor outcome. In those patients, the use of anti-IFN-λ 3, TLL1 and DDR1 therapy may be promising for personalized translational clinical practice.