Distichiasis in association with entropion in metastatic HER2-positive breast cancer treated by pertuzumab, trastuzumab, and docetaxel combination chemotherapy.
Faruk TasCan OzturkerPublished in: The breast journal (2019)
We report the first case of distichiasis combined with entropion in a HER2-positive metastatic breast cancer patient treated by pertuzumab, trastuzumab, and docetaxel combination therapy. After 7 months, she had ocular complaints including pain, irritation, burning, dryness, and redness in her both eyes. Ophthalmologic examination revealed distichiasis and a mild entropion involving her lower eyelids bilaterally. She remained free of symptom and in complete response to maintenance chemotherapy.
Keyphrases
- metastatic breast cancer
- combination therapy
- locally advanced
- positive breast cancer
- squamous cell carcinoma
- rectal cancer
- chronic pain
- epidermal growth factor receptor
- small cell lung cancer
- radiation therapy
- case report
- pain management
- optical coherence tomography
- single cell
- chemotherapy induced
- spinal cord
- patient reported