Ru(II)-Catalyzed Synthesis of Substituted Furans and Their Conversion to Butenolides.
Marie El ArbaSara E DibrellFrederick MeeceJonathan R NitschkePublished in: Organic letters (2018)
The synthesis of densely functionalized trisubstituted and tetrasubstituted furans via a novel Ru(II)-catalyzed intramolecular cyclization of vinyl diazoesters is reported. The synthetic utility of these furans is further demonstrated through a simple acid-mediated reaction to access highly substituted Δα,β-butenolides.