Login / Signup

Genetic diversity and population structure of Plasmodium falciparum in Nigeria: insights from microsatellite loci analysis.

Fehintola V AjogbasileAdeyemi T KayodePaul E OluniyiKazeem O AkanoJessica N UwanibeBenjamin B AdegboyegaCourage PhilipOluwagboadurami G JohnPhilomena J EromonGeorge EmechebeFinimo FinimoNnenna OgbulaforNma JiyaUche OkaforJose AmbeRobinson D WammandaStephen OgucheOlugbenga A MokuoluAkintunde SowunmiOnikepe A FolarinChristian T Happi
Published in: Malaria journal (2021)
The high level of parasite genetic diversity and low population structuring in this study suggests that parasite populations circulating in Nigeria are homogenous. However, higher resolution methods, such as the 24 SNP barcode and whole genome sequencing, may capture more specific parasite genetic signatures circulating in the country. The results obtained can be used as a baseline for parasite genetic diversity and structure, aiding in the formulation of appropriate therapeutic and control strategies in Nigeria.
Keyphrases
  • genetic diversity
  • plasmodium falciparum
  • genome wide
  • drug delivery
  • toxoplasma gondii
  • gene expression
  • copy number
  • single molecule
  • life cycle
  • genome wide association study