3D MR fingerprinting-derived myelin water fraction characterizing brain development and leukodystrophy.

Hyun Gi KimDongyeob HanJimin KimJeong-Sun ChoiKyung-Ok Cho

Published in: Journal of translational medicine (2023)

MWF demonstrated associations with histologic myelin quantity, age, and the presence of leukodystrophy, underscoring the potential of 3D MRF-derived MWF as a rapid and noninvasive quantitative indicator of brain myelin content in both mice and humans.

Keyphrases

white matter
multiple sclerosis
resting state
functional connectivity
magnetic resonance
high fat diet induced
type diabetes
magnetic resonance imaging
contrast enhanced
metabolic syndrome
mass spectrometry
brain injury
quantum dots
human health
wild type
sensitive detection