Discontinuation of tofacitinib and TNF inhibitors in patients with rheumatoid arthritis: analysis of pooled data from two registries in Canada.

Mohammad MovahediDenis ChoquetteLouis CoupalAngela CestaXiuying LiEdward C KeystoneClaire BombardierObri Investigators

Published in: BMJ open (2023)

In this pooled real-world data study, the discontinuation rates overall were similar. However, discontinuation due to AEs was higher in TOFA compared with TNFi users.

Keyphrases

rheumatoid arthritis
electronic health record
big data
clinical trial
machine learning
ulcerative colitis
artificial intelligence