Targeted Mutational Analysis of Cortisol-Producing Adenomas.

Juilee RegeJessie HoxieChia-Jen LiuMorgan N CashJames M LutherLan GellertAdina F TurcuTobias ElseThomas J GiordanoAaron M UdagerWilliam E RaineyKazutaka Nanba

Published in: The Journal of clinical endocrinology and metabolism (2021)

Comprehensive FFPE IHC-guided gene-targeted sequencing approach identified somatic mutations in 71.8% of the CPA. OCS-CPA demonstrated a distinct mutation profile compared to MACE-CPA.

Keyphrases

cancer therapy
copy number
genome wide
single cell
drug delivery
gene expression
dna methylation