Epacadostat Plus Pembrolizumab and Chemotherapy for Advanced Solid Tumors: Results from the Phase I/II ECHO-207/KEYNOTE-723 Study.
John D PowderlySamuel J KlempnerAung NaingJohanna BendellIgnacio Garrido-LagunaDaniel V T CatenacciMatthew H TaylorJames J LeeFred ZhengFeng ZhouXiaohua GongHema GowdaGregory L BeattyPublished in: The oncologist (2022)
The combination of epacadostat 100 mg bid with pembrolizumab and chemotherapy had an acceptable safety profile. This regimen showed antitumor activity across multiple types of advanced or metastatic solid tumors (ClinicalTrials.gov Identifier: NCT03085914).