Total tau in cerebrospinal fluid detects treatment responders among spinal muscular atrophy types 1-3 patients treated with nusinersen.
Goran ŠimićVana VukićMarija BabićMaria BanovićIvana BerečićEna ŠpanićKlara ZubčićAnja Tea GolubićMarija Barišić KutijaAna Merkler ŠorgićŽeljka VogrincIvan LehmanPatrick R HofJadranka SertićNina BarišićPublished in: CNS neuroscience & therapeutics (2022)
The measurement of total tau concentration in CSF is a reliable index for monitoring the biomarker and clinical response to nusinersen therapy in patients with SMA.