Should an Age Cutoff Be Considered for Elective Total Knee Arthroplasty Patients? An Analysis of Operative Success Based on Patient-Reported Outcomes.
Joshua A BellAhmed K EmaraWael K BarsoumMichael BloomfieldIsaac BriskinCarlos HigueraAlison K KlikaViktor E KrebsNathan W MeskoRobert M MolloyMichael A MontTrevor G MurrayGeorge F MuschlerRobert J NickodemPreetesh D PatelJonathan L SchafferKim L StearnsGregory J StrnadNicolas Santiago PiuzziPublished in: The journal of knee surgery (2022)
Total knee arthroplasty (TKA) is increasing in the elderly population; however, some patients, family members, and surgeons raise age-related concerns over expected improvement and risks. This study aimed to (1) evaluate the relationship between age and change in patient-reported outcome measures (PROMs); (2) model how many patients would be denied improvements in PROMs if hypothetical age cutoffs were implemented; and (3) assess length of stay (LOS), readmission, reoperation, and mortality per age group. A prospective cohort of 4,396 primary TKAs (August 2015-August 2018) was analyzed. One-year PROMs were evaluated via Knee injury and Osteoarthritis Outcome Score (KOOS)-pain, -physical function short form (-PS), and -quality of life (-QOL), as well as Veterans Rand-12 (VR-12) physical (-PCS) and mental component (-MCS) scores. Positive predictive values (PPVs) of the number of postoperative "failures" (i.e., unattained minimal clinically important difference in PROMs) relative to number of hypothetically denied "successes" from a theoretical age-group restriction was estimated. KOOS-PS and QOL median score improvements were equivalent among all age groups ( p = 0.946 and p = 0.467, respectively). KOOS-pain improvement was equivalent for ≥80 and 60-69-year groups (44.4 [27.8-55.6]). Median VR-12 PCS improvements diminished as age increased (15.9, 14.8, and 13.4 for the 60-69, 70-79, and ≥80 groups, respectively; p = 0.002) while improvement in VR-12 MCS was similar among age groups ( p = 0.440). PPV for failure was highest in the ≥80 group, yet remained <34% for all KOOS measures. Overall mortality was highest in the ≥80 group (2.14%, n = 9). LOS >2, non-home discharge, and 90-day readmission were highest in the ≥80 group (8.11% [ n = 24], p < 0.001; 33.7% [ n = 109], p < 0.001; and 34.4% [ n = 111], p = 0.001, respectively). Elderly patients exhibited similar improvement in PROMs to younger counterparts despite higher LOS, non-home discharge, and 90-day readmission. Therefore, special care pathways should be implemented for those age groups.
Keyphrases
- patient reported outcomes
- total knee arthroplasty
- end stage renal disease
- patient reported
- healthcare
- chronic kidney disease
- newly diagnosed
- chronic pain
- physical activity
- patients undergoing
- total hip
- peritoneal dialysis
- type diabetes
- spinal cord injury
- pain management
- cardiovascular disease
- risk factors
- climate change
- mental health
- neuropathic pain
- cardiovascular events
- quality improvement
- coronary artery disease