Assessment of the protective effect of KN-93 drug in systemic epilepsy disorders induced by pilocarpine in male rat.

Fatemeh EbrahimiSeyed Shahabeddin SadrMehrdad RoghaniSafoura KhamseSaeed Mohammadian HaftcheshmehMojdeh Navid HamidiParvaneh Mohseni-MoghaddamMohsen Parviz

Published in: Journal of cellular biochemistry (2019)

Overall, our findings suggest that KN-93 can effectively suppress oxidative stress and inflammation. Furthermore, KN-93 is able to attenuate seizure behaviors by preventing its effects on neuron loss, so, it is valuable for the treatment of epileptic seizures.

Keyphrases

oxidative stress
temporal lobe epilepsy
dna damage
diabetic rats
ischemia reperfusion injury
induced apoptosis
emergency department
drug induced
adverse drug
electronic health record
heat shock
heat stress