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An integrative approach to identify sand fly vectors of leishmaniasis in Ethiopia by morphological and molecular techniques.

Myrthe PareynVit DvorakPetr HaladaNatalie Van HoutteNigatu GirmaWim de KeselBehailu MerdekiosFekadu MasseboHerwig LeirsPetr Volf
Published in: Parasites & vectors (2020)
Our study uses three complementary taxonomical methods for species identification of taxonomically challenging and yet medically import Ethiopian sand flies. The generated MALDI-TOF MS protein profiles resulted in unambiguous identifications, hence showing suitability of this technique for sand fly species identification. Furthermore, our results contribute to the still inadequate knowledge of the sand fly fauna of Ethiopia, a country severely burdened with human leishmaniasis.
Keyphrases
  • drinking water
  • drosophila melanogaster
  • endothelial cells
  • healthcare
  • mass spectrometry
  • bioinformatics analysis
  • induced pluripotent stem cells
  • genetic diversity
  • binding protein