Combined treatment with octreotide LAR and pegvisomant in patients with pituitary gigantism: clinical evaluation and genetic screening.

Ruth MangupliLiliya RostomyanEmilie CastermansJean-Hubert CabergPaul CamperosJaime KrivoyElvia CuauroVincent BoursAdrian F DalyAlbert Beckers

Published in: Pituitary (2017)

Treatment of pituitary gigantism is frequently challenging; delayed control increases the harmful effects of GH excess, such as, excessive stature and symptom burden, so early diagnosis and effective treatment are particularly important in these cases.

Keyphrases

clinical evaluation
growth hormone
gene expression
risk factors
physical activity
weight loss
weight gain
smoking cessation