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Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads.

Iñigo Prada-LuengoAnders KroghLasse MarettyBirgitte Regenberg
Published in: BMC bioinformatics (2019)
Circle-Map is an easy-to-use command line tool that implements the required pipeline to accurately detect circular DNA from circle enriched next generation sequencing experiments. Circle-Map is implemented in python3.6 and it is freely available at https://github.com/iprada/Circle-Map.
Keyphrases
  • sensitive detection
  • circulating tumor
  • high density
  • quantum dots
  • cell free
  • gene expression