Mapping child and adolescent self-reported symptom data to clinician-reported adverse event grading to improve pediatric oncology care and research.
Molly McFatrichJennifer BrondonNicole R LucasPamela S HindsScott H MaurerJennifer W MackDavid R FreyerShana S JacobsJustin N BakerCatriona MowbrayMian WangSharon M CastellinoAllison Barz LeahyBryce B ReevePublished in: Cancer (2019)
The current study provides a framework for integrating child self-reported symptom data directly into mandated AE reporting in oncology trials. Translating Pediatric PRO-CTCAE responses into clinically meaningful metrics will guide future cancer care and toxicity grading.