JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study.

Tom Le VoyerCyril GitiauxFrançois-Jérôme AuthierChristine BodemerIsabelle Melki Pierre Quartier Dit MaireFlorence AeschlimannArnaud IsapofJean Philippe HerbeuvalVincent BondetJean-Luc CharuelMarie-Louise FrémondDarragh DuffyMathieu P RoderoBrigitte Bader-Meunier

Published in: Rheumatology (Oxford, England) (2021)

JAKis resulted in a CID in a subset of new-onset or refractory patients with JDM and may dramatically reverse severe muscle vasculopathy. Overall tolerance was good except for a high rate of herpes zoster infection.

Keyphrases

interstitial lung disease
skeletal muscle
early onset
disease activity
drug induced