Could the Microbiota Be a Predictive Factor for the Clinical Response to Probiotic Supplementation in IBS-D? A Cohort Study.

Justine MarchixLucille QuénéhervéPhilippe BordronPhilippe AubertTony DurandThibauld OullierClaude BlondeauSamira Ait AbdellahStanislas Bruley des VarannesSamuel ChaffronEmmanuel CoronMichel Neunlist

Published in: Microorganisms (2023)

The multistrain probiotic improved the symptoms of IBS-D patients and induced distinct effects on the gut microbiota according to the patient's clinical response and initial microbiota composition. Our study further supports the need to develop individualised probiotic-based approaches regarding IBS.

Keyphrases

irritable bowel syndrome
end stage renal disease
ejection fraction
bacillus subtilis
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes
physical activity
stress induced