Concordance rate between oligoclonal bands and the Kappa index in patients with suspected multiple sclerosis (MS).

Renan Barros Domingues Márcio Vega Dos Santos Daiane Salomão Carlos Senne

Published in: Arquivos de neuro-psiquiatria (2024)

The KI and OCBs presented high concordance level. Currently, the detection of OCBs in the CSF is the standard method for MS diagnosis, but it is time-consuming, and its visual interpretation can be difficult. The results suggest that the KI is a good alternative for the detection of intrathecal immunoproduction in cases of suspected MS.

Keyphrases

multiple sclerosis
mass spectrometry
ms ms
loop mediated isothermal amplification
white matter
label free
real time pcr
neoadjuvant chemotherapy
nuclear factor
radiation therapy
toll like receptor
inflammatory response
immune response
quantum dots