Targeted capture sequencing identifies novel genetic variations in Chinese patients with idiopathic inflammatory myopathies.

Qing-Lin PengJin-Ming LinYong-Biao ZhangXue-Zhi ZhangPan-Pan WangTing-Ting WuJun YuXiao-Qun DongMing-Liang GuGuo-Chun Wang

Published in: International journal of rheumatic diseases (2018)

Our data have revealed novel genetic variations in the HLA region of IIM patients and provide new insight into the pathogenesis and diagnosis of IIMs.

Keyphrases

genome wide
end stage renal disease
newly diagnosed
ejection fraction
single cell
chronic kidney disease
oxidative stress
peritoneal dialysis
electronic health record
dna methylation
cancer therapy
gene expression
machine learning
big data