Biocompatibility assessment of single-walled carbon nanotubes using Saccharomyces cerevisiae as a model organism.
Song ZhuFei LuoJian LiBin ZhuGao-Xue WangPublished in: Journal of nanobiotechnology (2018)
O-SWCNTs can internalize in S. cerevisiae cells via direct penetration and endocytosis, and distribute in cytoplasm, vesicles, lysosomes and cell nucleus. Besides, O-SWCNTs (188.2 and 376.4 mg/L) can induce apoptosis in S. cerevisiae cells, and oxidative stress is involved in activation of the mitochondria-dependent apoptotic pathway.
Keyphrases
- cell cycle arrest
- induced apoptosis
- cell death
- oxidative stress
- saccharomyces cerevisiae
- endoplasmic reticulum stress
- walled carbon nanotubes
- pi k akt
- dna damage
- single cell
- stem cells
- ischemia reperfusion injury
- cell therapy
- cell proliferation
- mesenchymal stem cells
- diabetic rats
- anti inflammatory
- heat shock
- heat shock protein