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High functional allelic diversity and copy number in both MHC classes in the common buzzard.

Jamie WinternitzNayden ChakarovTony RinaudMeinolf OttensmannOliver Krüger
Published in: BMC ecology and evolution (2023)
We characterize and confirm the functionality of unexpectedly high copy number and allelic diversity in both MHC classes of a bird of prey. While balancing selection is acting on both classes, there is no evidence of differential selection pressure on MHC classes in common buzzards and this result may hold more generally once more data for understudied MHC exons becomes available.
Keyphrases
  • copy number
  • mitochondrial dna
  • genome wide
  • dna methylation
  • machine learning
  • deep learning
  • gene expression