Effect of 48 Months of Closed-Loop Insulin Delivery on Residual C-Peptide Secretion and Glycemic Control in Newly Diagnosed Youth With Type 1 Diabetes: A Randomized Trial.
Julia WareCharlotte K BoughtonJanet M AllenMalgorzata E WilinskaSara HartnellAjay ThankamonyTabitha RandellAtrayee GhatakRachel Elizabeth Jane BesserDaniela ElleriNicola TrevelyanFiona M CampbellJudy SibayanRyan BaileyPeter CalhounGareth J DunseathRoman Hovorkanull nullPublished in: Diabetes care (2024)
Improved glycemic control was sustained over 48 months after diagnosis with CL insulin delivery compared with standard therapy in youth with type 1 diabetes. This did not appear to confer a protective effect on residual C-peptide secretion.