Influence of hyperbaric oxygen on biomechanics and structural bone matrix in type 1 diabetes mellitus rats.

Pedro Henrique Justino Oliveira LimirioHuberth Alexandre da Rocha JuniorRicharlisson Borges de MoraisKaren Renata Nakamura HirakiAna Paula Coelho BalbiPriscilla Barbosa Ferreira SoaresPaula Dechichi

Published in: PloS one (2018)

Diabetes decreased collagen maturation and the mineral deposition process, thus reducing biomechanical properties. Moreover, the study showed that HBO improved crosslink maturation and increased maximum strength and stiffness in the femur of T1DM animals.

Keyphrases

bone mineral density
type diabetes
cardiovascular disease
glycemic control
finite element
postmenopausal women
metabolic syndrome
wound healing