Icariin protects cardiomyocytes against ischaemia/reperfusion injury by attenuating sirtuin 1-dependent mitochondrial oxidative damage.
Bing WuJian-Yu FengLi-Ming YuYan-Chun WangYong-Qing ChenYan WeiJin-Song HanXiao FengYu ZhangShou-Yin DiZhi-Qiang MaChong-Xi FanXiao-Qin HaPublished in: British journal of pharmacology (2018)
Pretreatment with icariin protected cardiomyocytes from I/R-induced oxidative stress through activation of sirtuin-1 /FOXO1 signalling.