BMSC-Derived Exosomes Attenuate Rat Osteoarthritis by Regulating Macrophage Polarization through PINK1/Parkin Signaling Pathway.

Beibei LiEnpu ShenZhiwen WuHui QiCheng'ai WuDanping LiuXu Jiang

Published in: Cartilage (2024)

BMSC-Exos ameliorate OA development by regulating synovial macrophage polarization, and one of the underlying mechanisms may be through inhibiting PINK1/Parkin signaling.

Keyphrases

signaling pathway
knee osteoarthritis
pi k akt
mesenchymal stem cells
epithelial mesenchymal transition
rheumatoid arthritis
induced apoptosis
stem cells
oxidative stress