The prognostic impact of RAS on overall survival following liver resection in early versus late-onset colorectal cancer patients.
Alexandre A JácomeTimothy J VreelandBenny JohnsonYoshikuni KawaguchiSteven H WeiY Nancy YouEduardo VilarJean-Nicolas VautheyCathy EngPublished in: British journal of cancer (2020)
Among patients undergoing CLM resection, RAS mutations have a greater negative influence on survival in patients with EOCRC, more so in patients ≤40 years, than in patients with LOCRC and should be considered as a prognostic factor in multidisciplinary treatment planning.