Analysis and Validation of Human Targets and Treatments Using a Hepatocellular Carcinoma-Immune Humanized Mouse Model.

Yue Zhao Jia Xu WangWai Nam LiuShin Yie FongTimothy Wai Ho ShuenMin LiuSarah HardenSue Yee TanJia Ying ChengWilson Wei Sheng TanJerry Kok Yen ChanCheng Ean CheeGuan Huei LeeHan Chong TohSeng Gee Lim Yue WanQingfeng Chen

Published in: Hepatology (Baltimore, Md.) (2022)

Humanized-immune-system HCC mouse models are suitable for identifying targets from cancer and immune components and for testing combinational therapies.

Keyphrases

mouse model
endothelial cells
monoclonal antibody
papillary thyroid
squamous cell
lymph node metastasis
childhood cancer