Increased Arterial Stiffness in Chronic Thromboembolic Pulmonary Hypertension Was Improved with Riociguat and Balloon Pulmonary Angioplasty: A Case Report.
Shuji SatoKazuhiro ShimizuTakuro ItoMasakazu TsubonoAkihiro OgawaTakeshi SasakiMao TakahashiMahito NoroKohji ShiraiPublished in: International medical case reports journal (2021)
These observations suggested that arterial stiffness as measured by CAVI was increased in CTEPH, potentially deteriorating cardiac function because of enhanced afterload. The mechanism of the increase of CAVI in this case of CTEPH was obscure; however, riociguat administration and BPA might improve the pathophysiology of CTEPH partly by decreasing CAVI.