Abnormal red blood cell morphological changes in thalassaemia associated with iron overload and oxidative stress.

Pornthip ChaichompooAriz QillahPornpan SirankaprachaJirada KaewchuchuenPoramate RimthongKittiphong PaiboonsukwongSuthat FucharoenSaovaros SvastiSuchin Worawichawong

Published in: Journal of clinical pathology (2019)

Iron overload and its consequent intracellular oxidative stress in RBCs were associated with reduce normocytes in patients with thalassaemia.

Keyphrases

oxidative stress
red blood cell
dna damage
diabetic rats
ischemia reperfusion injury
iron deficiency
induced apoptosis
reactive oxygen species
heat shock