Sentinel node restoration by vascularized lymph node transfer in mice.

Erika Guilpain KusajimaYuhei YamamotoKosuke IshikawaTakahiro MiuraEmi FunayamaMasayuki OsawaRyo TakagiTaku Maeda

Published in: Microsurgery (2022)

Metastasis decreased in mice with reconnected lymphatics after VLNT. A possible explanation was that lymphatic restoration may have contributed to the tumor immune response by allowing DC migration to LNs.

Keyphrases

lymph node
immune response
high fat diet induced
neoadjuvant chemotherapy
dendritic cells
sentinel lymph node
toll like receptor
metabolic syndrome
wild type
early stage
adipose tissue