Diagnostic accuracy of pre-operative breast magnetic resonance imaging (MRI) in predicting axillary lymph node metastasis: variations in intrinsic subtypes, and strategy to improve negative predictive value-an analysis of 2473 invasive breast cancer patients.
Shu-Tian ChenHung-Wen LaiJulia Huei-Mei ChangChiung-Ying LiaoTzu-Cheng WenWen-Pei WuHwa-Koon WuYing-Jen LinYu-Jun ChangShou-Tung ChenDar-Ren ChenHsin-I HuangChe-Lun HungPublished in: Breast cancer (Tokyo, Japan) (2023)
The diagnostic performance of MRI to predict ALN metastasis varied according to the intrinsic subtype. Combined pre-operative clinicopathologic factors and intrinsic subtypes may increase ALN MRI NPV, and further identify some groups of patients with low risks of ALN metastasis, high NPV, and low burdens of axillary disease even in false-negative cases.